ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,147, issued on March 24, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.).
"Rational polyploid adeno-associated virus vectors for the treatment of disease" was invented by Chengwen Li (Chapel Hill, N.C.) and Richard Jude Samulski (Hillsborough, N.C.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a polyploid adeno-associated virus (AAV) capsid, wherein the capsid comprises capsid protein VP1, wherein said capsid protein VP1 is from one or more than one first AAV serotype, wherein said capsid protein VP2 is from one or more than one first AAV serotype and capsid protein VP3, wherein sa...