US Patent Issued to The University of North Carolina at Chapel Hill on April 14 for "Methods and compositions for recombinant dengue viruses or vaccine and diagnostic development" (North Carolina Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,752, issued on April 14, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.).

"Methods and compositions for recombinant dengue viruses or vaccine and diagnostic development" was invented by Ralph Baric (Haw River, N.C.), Ellen Young (Hillsborough, N.C.) and Jennifer Munt (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that may introduce an epitope that is recognized by an antibody from a dengue virus se...