US Patent Issued to THE UNIVERSITY OF MASSACHUSETTS on Aug. 11 for "Cell culture methods" (Massachusetts, Minnesota Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,851, issued on Aug. 11, was assigned to THE UNIVERSITY OF MASSACHUSETTS (Boston).

"Cell culture methods" was invented by Seongkyu Yoon (Lowell, Mass.), Bingyu Kuang (Worcester, Mass.) and Duc Hoang (Burnsville, Minn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of cell culture includes (i) culturing cells in a cell culture medium, and (ii) maintaining at least one metabolite below an inhibitory concentration in the cell culture medium for the at least one metabolite, wherein the at least one metabolite is aconitic acid (AA), leucinic acid (HICA), cytidine monophosphate (CMP), methylsuccinic acid (MSA), trigonelline (TRI), N-acetylputresci...