US Patent Issued to The University of Chicago on July 14 for "One-step method for producing adenoviral vectors" (Illinois Inventor)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,110, issued on July 14, was assigned to The University of Chicago (Chicago).

"One-step method for producing adenoviral vectors" was invented by Tong-Chuan He (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure is directed to a gene transfer vector which comprises (i) all or part of a viral genome and (ii) a suicide gene flanked by unique cloning sequences. The disclosure also is directed to a system for producing an adenoviral vector comprising a destination vector comprising (i) all or part of an adenoviral genome and (ii) a suicide gene flanked by unique cloning sequences; a transgene flanked by unique cloning sequences; and (c)...