ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,866, issued on April 21, was assigned to THE UNIVERSITY OF CHICAGO (Chicago).
"Methods for the amplification of bisulfite-treated DNA" was invented by Chuan He (Chicago), Ji Nie (Chicago) and Xiao-Long Cui (Chicago).
According to the abstract* released by the U.S. Patent & Trademark Office: "The methods, compositions, and kits of the disclosure provide a novel approach for a whole genome, unbiased DNA analysis method that can be performed on limited amounts of DNA can be used to analyze DNA to determine its modification status. Aspects of the disclosure relate to a method for amplifying bisulfite-treated deoxyribonucleic acid (DNA) molecules comprising: (a) ligating an adaptor t...