US Patent Issued to The United States of America, as represented by the Secretary, Department of Health and Human Services on March 17 for "T cell receptors which recognize mutated EGFR" (Swedish, American Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,286, issued on March 17, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"T cell receptors which recognize mutated EGFR" was invented by Kenichi Hanada (Bethesda, Md.), Chihao Zhao (Bethesda, Md.), Anna Pasetto (Stockholm) and James C. Yang (Bethesda, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is an isolated or purified T cell receptor (TCR), wherein the TCR has antigenic specificity for a mutated EGFR amino acid sequence with a E746-A750 deletion. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vecto...