US Patent Issued to The United States of America, as represented by the Secretary, Department of Health and Human Services on July 7 for "T cell receptors recognizing HLA-CW8 restricted mutated KRAS" (Oregon, Maryland, Arkansas Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,981, issued on July 7, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"T cell receptors recognizing HLA-CW8 restricted mutated KRAS" was invented by Eric Tran (Portland, Ore.), Yong-Chen Lu (Little Rock, Ark.) and Steven A. Rosenberg (Potomac, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, re...