ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,558,424, issued on Feb. 24, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"T cells having enhanced anti-tumor activity" was invented by Warren J. Leonard (Bethesda, Md.), Dalton J. Hermans (Manitowoc, Wis.), Luca Gattinoni (Washington), Leonard M. Neckers (Bethesda, Md.), Sanjivan Gautam (Rockville, Md.) and Suman Mitra (Lambersart, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides compositions and methods for using adoptive cell therapy (ACT) for treating cancer in a mammal. Cultured T-cells are provided by (a) obtaining an isolated popu...