US Patent Issued to The Trustees of the University of Pennsylvania on Oct. 27 for "Anti-CD3 scFv and cytokine producing artificial antigen presenting cells" (Pennsylvania, New Jersey Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,316, issued on Oct. 27, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Anti-CD3 scFv and cytokine producing artificial antigen presenting cells" was invented by James L. Riley (Downingtown, Pa.), Gavin Ellis (Philadelphia), Jun Xu (Cherry Hill, N.J.) and Jan Melenhorst (Cherry Hill, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes compositions and methods for expanding T cells utilizing artificial antigen presenting cells (aAPCs) comprising a chimeric receptor molecule specific for CD3."

The patent was filed on Nov. 25, 2020, under Application No. 17/778,734.

*For further informati...