US Patent Issued to The Trustees of the University of Pennsylvania on May 12 for "Monoclonal antibodies against pathological tau, and methods of detection thereof" (Pennsylvania Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,095, issued on May 12, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Monoclonal antibodies against pathological tau, and methods of detection thereof" was invented by Garrett S. Gibbons (Philadelphia), Dawn M. Riddle (Philadelphia), John Q. Trojanowski (Philadelphia) and Virginia M.Y. Lee (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides monoclonal antibodies that selectively bind to pathological tau over native tau. In certain aspects, the antibodies inhibit or minimize propagation of tau aggregates and/or reduce spread of pathological tau in vivo. In other aspects, the dis...