US Patent Issued to The Trustees of the University of Pennsylvania on May 12 for "Compositions and methods of NKG2D chimeric antigen receptor T cells for controlling triple-negative breast cancer" (Pennsylvania Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,085, issued on May 12, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Compositions and methods of NKG2D chimeric antigen receptor T cells for controlling triple-negative breast cancer" was invented by Daniel Powell (Bala Cynwyd, Pa.) and De-Gang Song (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention includes a chimeric antigen receptor (CAR) specific for a natural-killer group 2, member D ligand (NKG2DL), compositions comprising the CAR, polynucleotides encoding the CAR, vectors comprising a polynucleotide encoding the CAR, and recombinant T cells comprising the CAR. The invention also include...