US Patent Issued to The Trustees of the University of Pennsylvania on Jan. 20 for "U1 snRNP regulates gene expression and modulates oncogenicity" (American, Japanese Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,054, issued on Jan. 20, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"U1 snRNP regulates gene expression and modulates oncogenicity" was invented by Gideon Dreyfuss (Wynnewood, Pa.), Lili Wan (Westfield, N.J.), Jung Min Oh (Philadelphia), Anna Maria Pinto (Philadelphia), Ihab Younis (Philadelphia), Michael George Berg (Northbrook, Ill.) and Daisuke Kaida (Toyama, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a method of regulating U1 activity associated with its splicing role as well as its role in protecting pre-mRNAs from premature termination by cleavage and polyadenylation, thereby ...