US Patent Issued to The Trustees of the University of Pennsylvania on April 7 for "Compositions for treating Friedreich's ataxia" (Pennsylvania, Maryland Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,348, issued on April 7, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Compositions for treating Friedreich's ataxia" was invented by James M. Wilson (Philadelphia), Christian Hinderer (Baltimore) and Nimrod Miller (Berwyn, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A recombinant adeno-associated virus (rAAV) comprising an AAV capsid and a vector genome comprising a frataxin gene is provided. Also provided is a composition containing an effective amount of rAAV to ameliorate symptoms of Freidreich's ataxia, including, e.g., reduction in progression towards neurocognitive decline and/or cardiomyopathy."

The p...