US Patent Issued to The Trustees of the University of Pennsylvania, The Regents of the University of California on June 23 for "Selective stimulation of T cells in solid tumors using oncolytic viral delivery of orthogonal IL-2" (Pennsylvania, California Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,661,401, issued on June 23, was assigned to The Trustees of the University of Pennsylvania (Philadelphia) and The Regents of the University of California (Oakland, Calif.).

"Selective stimulation of T cells in solid tumors using oncolytic viral delivery of orthogonal IL-2" was invented by Mikko Siurala (Philadelphia), Carl H. June (Merion Station, Pa.), Avery Posey (Philadelphia), Antoni Ribas (Los Angeles) and Anusha Kalbasi (Beverly Hills, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides orthogonal chimeric cytokine receptor/orthogonal cytokine pairs and compositions and methods for modified immune cells or precurs...