US Patent Issued to The Trustees of the University of Pennsylvania, George Mason Research Foundation on March 17 for "Ionizable lipids and methods of manufacture and use thereof" (Virginia Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,040, issued on March 17, was assigned to The Trustees of the University of Pennsylvania (Philadelphia) and George Mason Research Foundation Inc. (Fairfax, Va.).

"Ionizable lipids and methods of manufacture and use thereof" was invented by Michael Daro Buschmann (Fairfax, Va.), Mikell Paige (Fairfax, Va.), Suman Alishetty (Fairfax, Va.), Manuel Carrasco (Fairfax, Va.), Mohamad Gabriel Alameh (Fairfax, Va.) and Drew Weissman (Fairfax, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention encompasses novel ionizable lipids compounds and their use in lipid nanoparticles delivery systems that are useful in the delivery of nucleic acids to a m...