US Patent Issued to The Scripps Research Institute on Oct. 6 for "Disruption of CD28-sialoside ligand complexes to enhance T cell activation" (California Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,752,014, issued on Oct. 6, was assigned to The Scripps Research Institute (La Jolla, Calif.).

"Disruption of CD28-sialoside ligand complexes to enhance T cell activation" was invented by James C. Paulson (Del Mar, Calif.), Landon J. Edgar (San Diego), Andrew J. Thompson (San Diego), Chika Kikuchi (San Diego), Brett Garabedian (Del Mar, Calif.), Xiaoshuang Wang (San Diego) and Eleanor Bashian (Laguna Niguel, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods for enhancing T cell activation and expansion, and methods for stimulating a T cell immune response in a subject. The methods of the invention involve the use...