ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,712, issued on Feb. 10, was assigned to The Regents of the University of Michigan (Ann Arbor, Mich.).
"C3d cellular and acellular vaccines for the prevention and treatment of cancer" was invented by Marilia Cascalho (Ann Arbor, Mich.) and Jeffrey L. Platt (Ann Arbor, Mich.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the treatment of cancer and to the prevention of cancer growth and/or metastasis. In particular, the invention relates to cellular and acellular vaccines containing C3d, a proteolytic product of complement (C3), and methods of enhancing a host immune response (e.g., a T cell mediated immune response) a...