ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,128, issued on Sept. 8, was assigned to The Regents of the University of California (Oakland, Calif.).

"Compositions and methods for the treatment of neurological diseases and disorders" was invented by Varghese John (Los Angeles), Barbara Jagodzinska (Los Angeles), Patricia Spilman (Los Angeles), Jesus J. Campagna (Los Angeles), Kanagasabai Vadivel (Los Angeles) and Michael E. Jung (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "In certain embodiments allosteric inhibitors of BACE are provided. Illustrative inhibitors include but are not limited to various metformin analogs."

The patent was filed on May 13, 2020, under Application No. ...