ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,740,953, issued on Sept. 22, was assigned to The Regents of the University of California (Oakland, Calif.).
"Compositions comprising HDAC inhibitors and retinoids" was invented by Yu-Jui Yvonne Wan (Davis, Calif.), Kit S. Lam (Davis, Calif.) and Ruiwu Liu (Davis, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compositions and methods comprising conjugates with a polymeric backbone, e.g., polyvinyl alcohol (PVA), covalently linked histone deacetylase (HDAC) inhibitors, such as butyrate or propionate, and covalently linked retinoids, such as all-trans retinoic acid (RA). The methods and compositions of the invention ...