US Patent Issued to The Regents of the University of California on Sept. 15 for "Affinity-tagged photoswitches and methods of use thereof" (American, German Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,676, issued on Sept. 15, was assigned to The Regents of the University of California (Oakland, Calif.).

"Affinity-tagged photoswitches and methods of use thereof" was invented by Ehud Y. Isacoff (Berkeley, Calif.), Dirk Trauner (New York), Johannes Broichhagen (Heidelberg, Germany) and Joshua Levitz (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a conjugate comprising: a) an affinity agent that specifically binds a target ligand-binding polypeptide; and b) a photoisomerizable regulator comprising: i) a photoisomerizable moiety; and ii) a ligand that binds to the target ligand-binding polypeptide. The presen...