ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,333, issued on Oct. 27, was assigned to The Regents of the University of California (Oakland, Calif.).

"Compositions and methods for making and using multispecific antibodies" was invented by Bin Liu (San Francisco), Shanshan Lang (San Francisco), Yang Su (San Francisco), Scott Bidlingmaier (San Francisco) and Nam-Kyung Lee (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates generally to compositions and methods useful for the production of engineered antibodies having (i) multiple antigen-binding specificities and (ii) Fc regions that have been modified to promote heterodimer formation between heavy chains f...