US Patent Issued to The Regents of the University of California on Oct. 27 for "Compositions and methods for gene editing" (California Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,456, issued on Oct. 27, was assigned to The Regents of the University of California (Oakland, Calif.).

"Compositions and methods for gene editing" was invented by Jin Chen (San Francisco), Luke Gilbert (San Francisco), James Nunez (San Francisco) and Jonathan Weissman (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms. Provided herein also are fusion protein compositions that can turn off genes permanently and reversibly in mammalian cells using CRISPR-based epigenome editing. In addition, the methods provided herein include complexes...