ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,779,035, issued on Nov. 3, was assigned to The Regents of the University of California (Oakland, Calif.).
"Transplanted cell protection via inhibition of polymorphonuclear cells" was invented by Sonia Schrepfer (Burlingame, Calif.) and Tobias Deuse (Burlingame, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides, for the first time, strategies to inhibit the killing of transplanted cells by activated polymorphonuclear cells (PMNs) of the recipient. Multiple different modes for PMN inhibition are provided and one or more agents effectively utilized every mode of action. The combination of two or more of those agents with different...