US Patent Issued to The Regents of the University of California on May 26 for "Augmentations to lentiviral vectors (CCLC-MGATA/ANK-CORE LCR-BETA-AS3-FB) to increase expression" (California Inventors)

ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,696, issued on May 26, was assigned to The Regents of the University of California (Oakland, Calif.).

"Augmentations to lentiviral vectors (CCLC-MGATA/ANK-CORE LCR-BETA-AS3-FB) to increase expression" was invented by Donald B. Kohn (Tarzana, Calif.), Richard A. Morgan (Santa Monica, Calif.) and Roger Paul Hollis (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "In certain embodiments a lentiviral vector having an LCR comprising HS1 ENCODE core (EC1) sequence (SEQ ID NO:1), and one or more of an HS2 core sequence (ecHS2), an HS3 core sequence (ecHS3), an HS4 core sequence (ecHS4), a full length HS2, a full length HS3, and/or a full length HS...