ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,298, issued on March 31, was assigned to The Regents of the University of California (Oakland, Calif.).
"Ex vivo tumor angiogenesis model" was invented by Hui Sun (Los Angeles), Adrian Chichuen Au (Los Angeles) and Guo Cheng (Los Angeles).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates generally to ex vivo primary tumor models prepared from fresh tumor tissues which are useful for screening anti-cancer agents. The fresh tumor tissues are prepared and cultured under suitable conditions to grow an outgrowth of endothelial cells. Killing of these endothelial cells by a candidate agent indicates the efficacy of the agent in...