US Patent Issued to The Regents of the University of California on March 17 for "Cells for enhanced production of adeno-associated virus" (California Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,539, issued on March 17, was assigned to The Regents of the University of California (Oakland, Calif.).

"Cells for enhanced production of adeno-associated virus" was invented by David V. Schaffer (Danville, Calif.), Christopher Barnes (Oakland, Calif.) and David Stephen Ojala (Berkeley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides an in vitro mammalian cell that is genetically modified to provide for enhanced production of adeno-associated virus (AAV) virions. The mammalian cells can be used to produce AAV virions, e.g., recombinant AAV virions that include a heterologous nucleic acid encoding a gene product...