US Patent Issued to The Regents of the University of California on Feb. 24 for "Complement component 1s (C1s) deficient cells for production of vaccines and biopharmaceutical proteins" (California Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,526, issued on Feb. 24, was assigned to The Regents of the University of California (Oakland, Calif.).

"Complement component 1s (C1s) deficient cells for production of vaccines and biopharmaceutical proteins" was invented by Sophia Li (Santa Cruz, Calif.) and Phillip Berman (Santa Cruz, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure reports that a calcium-dependent serine protease, complement component is (C1s) has been identified as a protease responsive for cleavage of exogenous polypeptides expressed in mammalian cell lines such as CHO cells. These CHO cell lines provide for increased yield of antigenically correct, ...