US Patent Issued to The Regents of the University of California on Feb. 17 for "Polymeric nanoparticles that target liver sinusoidal endothelial cells to induce antigen-specific immune tolerance" (California Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,542, issued on Feb. 17, was assigned to The Regents of the University of California (Oakland, Calif.).

"Polymeric nanoparticles that target liver sinusoidal endothelial cells to induce antigen-specific immune tolerance" was invented by Andre E. Nel (Sherman Oaks, Calif.), Tian Xia (Los Angeles) and Qi Liu (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "In various embodiments tolerogenic nanoparticles are provided that induce immune tolerance to one or more desired antigen(s) and/or that reduce an immune response to those antigen(s). In certain embodiments the tolerogenic nanoparticle comprises a nanoparticle comprising a biocompatible po...