US Patent Issued to The Regents of the University of California on April 14 for "Methods for treating drug resistant cancers" (California Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,601,743, issued on April 14, was assigned to The Regents of the University of California (Oakland, Calif.).

"Methods for treating drug resistant cancers" was invented by David Cheresh (Encinitas, Calif.), Sara Weis (San Diego) and Erika Cosset (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods for determining whether a glioblastoma (GBM) tumor or GBM cancer cell will be sensitive to a treatment targeting the integrin avb3 (AlphavBeta3) pathway, comprising determining whether the GBM tumor or the GBM cancer cell expresses both avb3+ and Glut3+ along with a specific genetic signature associated with Glut3 addiction, whe...