US Patent Issued to The Medical College of Wisconsin, Lodz University of Technology on July 15 for "Targeting redox-active pyridinium cations to mitochondria to inhibit proliferation of drug-resistant cancer cells" (American, Polish Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,935, issued on July 15, was assigned to The Medical College of Wisconsin Inc. (Milwaukee) and Lodz University of Technology (Lodz, Poland).

"Targeting redox-active pyridinium cations to mitochondria to inhibit proliferation of drug-resistant cancer cells" was invented by Jacek Michal Zielonka (Wauwatosa, Wis.), Adam Bartlomiej Sikora (Lodz, Poland) and Balaraman Kalyanaraman (Milwaukee).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides novel mito-pyridinium compounds, prodrugs and the uses thereof for the treatment of cancer, particularly drug resistant cancer."

The patent was filed on Nov. 1, 2019, under Application No. ...