US Patent Issued to The Johns Hopkins University on Dec. 9 for "Bispecific binding agents" (Maryland Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,258, issued on Dec. 9, was assigned to The Johns Hopkins University (Baltimore).

"Bispecific binding agents" was invented by Jamie Spangler (Baltimore), Denis Gaston Wirtz (Baltimore), Huilin Yang (Baltimore), Wentao Wang (Baltimore) and Michelle Karl (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are novel bispecific binding agents and methods of constructing and expressing the same. The methods of constructing the bispecific binding agent generally describes a combination of a knobs-in-holes assembly strategy and a single-chain Fab expression approach to generate a modular bispecific binding platform."

The patent was fil...