US Patent Issued to The Johns Hopkins University on Aug. 25 for "Composition of shelf-stable plasmid dna/polyethyleneimine (pei) particles with defined sizes for viral vector production and method for preparation of the same" (Maryland Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,716,073, issued on Aug. 25, was assigned to The Johns Hopkins University (Baltimore).

"Composition of shelf-stable plasmid dna/polyethyleneimine (pei) particles with defined sizes for viral vector production and method for preparation of the same" was invented by Hai-Quan Mao (Baltimore), Yining Zhu (Baltimore) and Yizong Hu (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "A scalable method for producing DNA/polycation particles having an optimal, defined particle size with multiple virus assembly plasmids for efficient transfection of viral production cells in suspension cultures. The presently disclosed DNA/polycation particles yield superior...