US Patent Issued to The Institute of Cancer Research: Royal Cancer Hospital on July 7 for "Anti-cancer vaccines and related therapy" (British Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,179, issued on July 7, was assigned to The Institute of Cancer Research: Royal Cancer Hospital (London).

"Anti-cancer vaccines and related therapy" was invented by Stephen Pettitt (London), Christopher Lord (London), Marco Punta (London) and Alan Melcher (London).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an anti-cancer vaccine comprising: (i) at least one peptide comprising the amino acid sequence of a neoantigen encoded by a mutant homologous recombination (HR) DNA repair gene selected from the group: BRCA1, BRCA2, PALB2, CDK12, RAD51B, RAD51C and RAD51D, wherein the mutant gene comprises a reversion mutation; and/...