US Patent Issued to The Henry M. Jackson Foundation for the Advancement of Military Medicine on July 28 for "SETBP1 and XPO1 inhibitors for the treatment of sickle cell disease and Beta-thalassemia" (Maryland Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,116, issued on July 28, was assigned to The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. (Bethesda, Md.).

"SETBP1 and XPO1 inhibitors for the treatment of sickle cell disease and Beta-thalassemia" was invented by Yang Du (Gaithersburg, Md.), Nhu Nguyen (Rockville, Md.) and Kristbjorn Gudmundsson (Silver Spring, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compounds that inhibit SETBP1 or XP01 activities. Also disclosed are methods of using such compounds to increase the expression of embryonic and fetal hemoglobin molecules, and to treat sickle cell disease and Beta-thalassemia. Th...