ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,892, issued on July 21, was assigned to THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto).
"Molecular sensing platform and methods of use" was invented by Margot Karlikow (Toronto), Keith Pardee (Toronto) and Peivand Sadat Mousavi (Waterloo, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are signal-inducing CRISPR-sensitive nucleic acid, optionally DNA, sensors, for example comprising: a) a non-functional CRISPR-sensitive DNA reporter construct comprising a non-functional expression cassette with at least one CRISPR target site inserted, generated by removal or addition of nucleic acids or naturally present in the expressi...