US Patent Issued to The General Hospital on Sept. 2 for "Using micrornas to control activation status of hepatic stellate cells and to prevent fibrosis in progressive liver diseases" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,507, issued on Sept. 2, was assigned to The General Hospital Corp..

"Using micrornas to control activation status of hepatic stellate cells and to prevent fibrosis in progressive liver diseases" was invented by Michael Yoonsuk Choi (Boston) and Byeong-Moo Kim (Wellesley, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods and compositions for treatment and/or prevention of liver disease. Aspects of the present disclosure relate to the engineering of a quiescent Hepatic Stellate Cell, and use of the engineered quiescent Hepatic Stellate Cell, or population thereof in the treatment and/or prevention of liver disease."

The...