US Patent Issued to The General Hospital on Sept. 15 for "FUS/TLS-based compounds and methods for diagnosis, treatment and prevention of amyotrophic lateral sclerosis and related motor neuron diseases" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,745, issued on Sept. 15, was assigned to The General Hospital Corp. (Boston).

"FUS/TLS-based compounds and methods for diagnosis, treatment and prevention of amyotrophic lateral sclerosis and related motor neuron diseases" was invented by Thomas J. Kwiatkowski Jr. (Cambridge, Mass.) and Robert H. Brown Jr. (Needham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides novel FUS/TLS nucleic acids and proteins that comprise one or more genetic markers (for example, single nucleotide polymorphisms) and methods of use thereof including methods relating to the diagnosis of ALS or other related motor neuron disease by virtue of the...