ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,188, issued on March 3, was assigned to The General Hospital Corp. (Boston).

"Hydrogel beads for controlled uptake and release of cryoprotective agents" was invented by Derin Sevenler (Cambridge, Mass.), Rebecca Sandlin (Melrose, Mass.) and Mehmet Toner (Charlestown, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Hydrogel beads having tunable rates of loading and unloading of cryoprotective agents are provided herein. Such hydrogel beads can be dispersed throughout a cell suspension to enable loading and unloading of cryoprotective agents from cells in a gradual and distributed manner that protects the cells from osmotic damage. Lymphocyte via...