ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,403, issued on Feb. 10, was assigned to The General Hospital Corp. (Boston).
"Methods to treat mitochondrial-associated dysfunctions or diseases" was invented by Vamsi K. Mootha (Boston), Warren M. Zapol (Cambridge, Mass.), Isha Jain (Cambridge, Mass.) and Luca Zazzeron (Boston).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for the treatment of disorders associated with mitochondrial dysfunction, including rare, inborn errors of metabolism caused by genetic mutations; neurodegenerative disease; diabetes; and aging and age-associated decline. Generally, the methods include administering a therapeutically effective amount of one or more treatm...