US Patent Issued to The General Hospital on April 7 for "Antibodies and chimeric antigen receptors that target TACI" (Massachusetts Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,303, issued on April 7, was assigned to The General Hospital Corp. (Boston).

"Antibodies and chimeric antigen receptors that target TACI" was invented by Marcela V. Maus (Lexington, Mass.) and Rebecca Larson (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides antibodies, antibody-drug conjugates, bispecific T cell engagers (BiTEs), and chimeric antigen receptors (CARs) that target transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI). Such antibodies, antibody-drug conjugates, BiTEs, and CARs can be used, e.g., in methods for treating a cancer (e.g., multiple myeloma), an autoimmune disorder...