US Patent Issued to The General Hospital, MASSACHUSETTS EYE AND EAR INFIRMARY on Dec. 16 for "Modified Mullerian Inhibiting Substance (MIS) proteins and uses thereof for the treatment of diseases" (Massachusetts Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,437, issued on Dec. 16, was assigned to The General Hospital Corp. and MASSACHUSETTS EYE AND EAR INFIRMARY.

"Modified Mullerian Inhibiting Substance (MIS) proteins and uses thereof for the treatment of diseases" was invented by Patricia K. Donahoe (Boston), Demetrios Vavvas (Boston), David Pepin (Somerville, Mass.) and Mien Van Hoang (Braintree, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to modified recombinant human MIS protein which has improved cleavage and increased bioactivity and increased potency as compared to wild-type human MIS protein. Other aspects of the invention relate to methods to prevent and ...