US Patent Issued to The General Hospital, Children's Medical Center on July 15 for "Efficient protein expression in vivo using modified RNA (mod-RNA)" (Massachusetts Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,675, issued on July 15, was assigned to The General Hospital Corp. and Children's Medical Center Corp..

"Efficient protein expression in vivo using modified RNA (mod-RNA)" was invented by Kenneth R. Chien (Cambridge, Mass.), Leon M. Ptaszek (Newton, Mass.), Kathy Oi-Lan Lui (Boston), Lior Zangi (Brookline, Mass.), Wataru Ebina (Boston) and Derrick J. Rossi (Roslindale, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the invention described herein relate to synthetic, modified RNAs and their use in vivo to modulate gene expression. Aspects of the invention further relate to the use of these synthetic, modified RNAs in myocytes, cardio...