ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,323, issued on Oct. 27, was assigned to The General Hospital Corp. (Boston), Banner Health (Boston) and Massachusetts Eye and Ear Infirmary (Boston).

"Anti-apolipoprotein e (APOE) antibodies and polynucleotides thereof" was invented by Yakeel T. Quiroz (Charlestown, Mass.), Joseph F. Arboleda-Velasquez (Newton, Mass.), Eric Reiman (Phoenix) and Francisco Lopera (Medellin, Colombia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions for preventing or treating cognitive decline associated with dementia and/or mild cognitive impairment and/or neurodegeneration using antibodies, peptides, fusion proteins, or genome editing systems th...