US Patent Issued to THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES on Feb. 24 for "Bacterial DNA gyrase inhibitors and methods of use thereof" (Florida Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,558,366, issued on Feb. 24, was assigned to THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami).

"Bacterial DNA gyrase inhibitors and methods of use thereof" was invented by Fenfei Leng (Palmetto Bay, Fla.), Eddy Alfonso (Miami) and Zifang Deng (Miami).

According to the abstract* released by the U.S. Patent & Trademark Office: "The subject invention provides fluorophore-quencher nucleic acid molecules comprising relaxed or supercoiled DNA molecules, and their use in rapid and efficient high-throughput screening (HTS) assays to screen and identify compounds that inhibit DNA gyrases. These compounds can be used as antibiotics for treating bacterial infections, especially, mu...