US Patent Issued to The Cleveland Clinic Foundation on Oct. 20 for "Protease inhibitors and methods of use" (Ohio Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,766,134, issued on Oct. 20, was assigned to The Cleveland Clinic Foundation (Cleveland).

"Protease inhibitors and methods of use" was invented by Shaun R. Stauffer (Cleveland), Jonathan D. Macdonald (Cleveland), Alice Hooper (Cleveland), Sang Hoon Han (Cleveland), Dhiraj P. Sonawane (Cleveland), Matthew R. Porter (Cleveland), Joshua Maw (Cleveland), Steven Martinez (Cleveland) and Joseph Alvarado (Cleveland).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compounds that inhibit the 3C-like protease of SARS-CoV-2. Also disclosed herein are pharmaceutical compositions comprising the compounds, and methods of using the compounds, e.g., i...