US Patent Issued to The Chinese University of Hong Kong on March 17 for "Ph-reversible leuco-BODIPY probe for in situ visualization of extracellular vesicles and their secretion from living cells" (Chinese Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,578,273, issued on March 17, was assigned to The Chinese University of Hong Kong (Hong Kong).

"Ph-reversible leuco-BODIPY probe for in situ visualization of extracellular vesicles and their secretion from living cells" was invented by Chung Hang Jonathan Choi (Hong Kong) and Hanzhuang Liu (Dalian City, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The subject invention pertains to compositions of a probe comprising two pH-reversible forms, including the boron dipyrromethene (BODIPY) fluorescent form and the non-fluorescent leuco-BODIPY form, for use in confocal imaging methods of intracellular vesicles as well as extracellular vesicles that are ...