ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,311, issued on March 31, was assigned to THE CHILDREN'S MEDICAL CENTER Corp..
"Methods and compositions for the treatment of cancer" was invented by Judy Lieberman (Brookline, Mass.) and Ying Zhang (Boston).
According to the abstract* released by the U.S. Patent & Trademark Office: "The technology described herein is directed to improved chimeric molecules for, e.g, the treatment of cancer. As described herein, the inventors have developed novel chimeric aptamer-siRNA molecules (AsiCs) which demonstrate improved efficacy over existing AsiCs and which can successfully synergize in treating cancer. These AsiC's target cancer cell markers to direct therapeutic siRNA molecules speci...