US Patent Issued to The Children's Medical Center, Dana-Farber Cancer Institute on March 17 for "Methods and compositions for reconstituting microglia" (Massachusetts Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,110, issued on March 17, was assigned to The Children's Medical Center Corp. (Boston) and Dana-Farber Cancer Institute Inc. (Boston).

"Methods and compositions for reconstituting microglia" was invented by Alessandra Biffi (Boston) and Annita Montepeloso (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure features CX3CR1 hemizygous and/or homozygous defective cells and methods of using such cells for the treatment of a metabolic or neurological disorder. The disclosed methods include methods for making and modifying CX3CR1 hemizygous and/or homozygous defective cells, such as hematopoietic stem progenitor cells. Other disc...