US Patent Issued to The Children's Hospital of Philadelphia on Oct. 14 for "Antibodies for the diagnosis and treatment of B-cell acute lymphoblastic leukemia" (Pennsylvania Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,794, issued on Oct. 14, was assigned to The Children's Hospital of Philadelphia (Philadelphia).

"Antibodies for the diagnosis and treatment of B-cell acute lymphoblastic leukemia" was invented by Andrei Thomas-Tikhonenko (Philadelphia) and Sisi Zheng (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure is directed to antibodies binding to CD22-Del.ex5-6 protein and methods of using such antibodies to treat cancers that express or overexpress CD22-Del.ex5-6 protein. Specifically, the disclosure provides a method of treating cancer comprising contacting a cancer cell in a subject with an antibody or antibody derivative t...