US Patent Issued to The Broad Institute, Massachusetts Institutes of Technology on Sept. 15 for "Three-dimensional human neural tissues for CRISPR-mediated perturbation of disease genes" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,736,526, issued on Sept. 15, was assigned to The Broad Institute Inc. (Cambridge, Mass.) and Massachusetts Institutes of Technology (Cambridge, Mass.).

"Three-dimensional human neural tissues for CRISPR-mediated perturbation of disease genes" was invented by Halil Tekin (Cambridge, Mass.) and Feng Zhang (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are tissue cultures and methods for culturing stem-cell derived neurons in three-dimensional culture. Also provided are methods for screening therapeutic agents, developing cell line models, identifying genes associated with a neurological disease, and identifying genes as...